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. 1999 Feb 16;96(4):1291–1296. doi: 10.1073/pnas.96.4.1291

Table 1.

FBP levels and the quarternary structure of M2-PK in E7-expressing NIH3T3 cells

Cell type FBP, nmole/ mg protein Tetramer, % Dimer, %
M/1 0.22  ± 0.04 63.5  ± 0.3 36.5  ± 0.6
Δ79-83 0.40  ± 0.10n.s. 59.9  ± 1.6n.s. 40.1  ± 1.6n.s.
E7/2 0.40  ± 0.04 47.2  ± 0.9 52.8  ± 0.8
 (P < 0.05)  (P < 0.001)  (P < 0.001)

Control and E7-expressing NIH3T3 subclones were used for gel filtration analysis of M2-PK as indicated; the results are given as the relative amounts of the tetrameric and dimeric forms of M2-PK (Inline graphic ± SEM, n = 4). FBP levels were determined in perchloric acid extracts. Inline graphic ± SEM, n = 5. n.s., not significant.