TABLE 6.
Most common virulence profiles of STEC strains and their distribution by the clinical pictures of 170 subjects
| Virulence profile | Phenotype and genotype | Total no. of subjects (n = 170a) | No. of subjects with: |
Other bacterial characteristics |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| HUS or TTP (n = 20b) | Bloody diarrhea (n = 77c) | Nonbloody diarrhea (n = 37) | Asymptomatic (n = 26d) | Not known (n = 10) | eae positive | Ehly positive | Stx titer of ≥128 | |||
| P1 | O157:H7:PT2:stx2:stx2c | 55 | 9e | 30 | 8 | 7 | 1 | 55 | 55 | 55 |
| P2 | O145:H28/H−:stx2 | 7 | 3b | 3c | 0 | 1 | 0 | 7 | 6 | 3 |
| P3 | O157:H7/H−:PT88:stx2 | 4 | 1b | 0 | 0 | 1 | 2 | 4 | 0 | 0 |
| P4 | O157:H7:PT49:stx2:stx2c | 10 | 1 | 5 | 2 | 2 | 0 | 10 | 10 | 10 |
| P5 | O157:H7:PT2:stx2 | 4 | 1 | 3 | 0 | 0 | 0 | 4 | 4 | 4 |
| P6 | O103:H2/H−:stx1 | 13 | 0 | 5 | 6 | 1 | 1 | 12 | 13 | 5 |
| P7 | O157:H7/H−:PT8:stx1 and stx2 or stx2 variantf | 8 | 0 | 4 | 2 | 1 | 1 | 8 | 6 | 5 |
| P8 | O157:H7:PT4:stx2 | 7 | 0 | 3 | 3 | 1 | 0 | 7 | 7 | 7 |
| P9 | O26:H11/H−:stx1 | 7 | 0 | 4 | 0 | 2 | 1 | 7 | 6 | 1 |
| P10 | O157:H7:PT4:stx2:stx2c | 5 | 0 | 4 | 1 | 0 | 0 | 5 | 5 | 5 |
| Other O157 | 18 | 0 | 5c | 10 | 1 | 2 | 18 | 14 | 13 | |
| Other non-O157 | 35 | 6g | 12h | 5i | 10d,j | 2k | 14 | 18 | 11 | |
Three patients had infections with STEC O157 and non-O157 strains (the number of isolates is then 173).
One patient had a simultaneous infection with O157:H−:PT88:stx2 and O145:H28:stx2 (the number of isolates is then 21).
One patient had a simultaneous infection with O157:H−:PT88 lacking stx and O145:H28:stx2 (the number of isolates is then 78).
One patient had consecutive infection with O102:H7:undigestible and O Rough:H18:undigestible (the number of isolates is then 27).
Two patients in the age group of 1 to 5 years died.
stx2 variants were stx2c (five strains), stx2vhb (two strains), and stx2 and stx2vhb (one strain).
The corresponding virulence profiles were (one strain each) OX174:H21:stx2c, O Rough:H4:stx2c, O101:H−:stx2, O Rough:H49:stx2c, O107:H27 lackin g stx, and O2:H29:undigestible.
The corresponding virulence profiles were (one strain each) O156:H25:stx1, O15:H−:stx1, OX181:H49:stx2:stx2c, OX174:H21:stx2vhb, OX174:H2:stx2vhb, O165:H25:stx2, O103:H2:stx2, O91:H40:stx1:stx2c, O Rough:H−:stx1, O Rough:H−:stx2d-Ount, O8:H9:stx2vhb, and O20:H7:stx2c.
The corresponding virulence profiles were (one strain each) O76:H19:stx2d-Ount, O15:H−:stx2, O91:H21:stx2:stx2vhb, O111:H8:stx1 , ONT:H33:weak positive in PCR.
The corresponding virulence profiles were O Rough:H2:stx2 (one strain), O15:H−:stx1 (one strain), O103:H2:stx2 (two strains), O Rough:H21:weak positive in PCR (one strain), O Rough:H4:stx2 (two strains), O116:H21:stx2 (one strain), O102:H7:undigestible (one strain), and O Rough:H18:undigestible (one strain).
The corresponding virulence profiles were O43:H2:stx1 and O Rough:H−:stx1.