Figure 2.

Amino acid sequence and hydropathy analysis of the XPR1 protein. Predicted transmembrane segments are underlined, and potential consensus N-glycosylation sites are indicated by filled circles. The glycosylation site NIT at position 248 is located in the first predicted transmembrane segment. The hydropathy plot of XPR1 was generated by the program of Kyte and Doolittle (38) by using a window of 11 residues. Positive values indicate hydrophobic region, and negative values indicate hydrophilic regions.