TABLE 2.
Genotypic characteristics of H. pylori isolates from Dhaka, Bangladesh, and relation to disease status
| Trait or markera | No. of patients with indicated disease status
|
|
|---|---|---|
| PU (n = 37 [64%]) | NUD (n = 20 [36%]) | |
| cag PAI+ onlyb | 28 | 11 |
| cag PAI+, cag PAI− mixedb | 3 | 4 |
| cag PAI− onlyb | 6 | 5 |
| vacAs1 only | 30 | 12 |
| vacAs2 | 6 | 6 |
| vacAs1, vacAs2 mixed | 1 | 2 |
| vacAm1c | 22 | 8 |
| vacAm2 only | 13 | 8 |
| vacAm1c, vacAm2 mixed | 2 | 4 |
| iceA1c | 19 | 9 |
| iceA2 | 17 | 10 |
| iceA1, iceA2 mixed | 1 | 1 |
| IS605 | 16 | 7 |
| IS606 | 11 | 7 |
| IS608 | 6 | 3 |
| cag type IIId | 26 | 11 |
| cag type IId | 1 | 0 |
| cag type Id | 4 | 3 |
a
Distribution of DNA markers was determined by PCR, as illustrated in the figures.
b
cag PAI+ only, infection with strains carrying cag PAI only; cag PAI+, cag PAI− mixed infection with strains carrying the cag PAI and strains lacking the cag PAI; cag PAI− only, infection with strains lacking the cag PAI only.
c
A 94-bp deletion was found in two isolates, both from patients with PU.
d
The 3′ end of the cag gene was typed and scored as type I, II, or III. Isolates from European origin usually belong to type I.