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. 2003 May;41(5):1875–1880. doi: 10.1128/JCM.41.5.1875-1880.2003

TABLE 2.

Overall interpretive agreement between results of fluconazole and voriconazole agar-based susceptibility tests and of standard 48-h BMD reference tests for 235 C. glabrata isolates

Antifungal agent Method and mediuma % of isolates by categoryb
% of discrepant resultsc
% Categorical agreementd
S S-DD R Minor Major Very major
Fluconazole BMD 57 36 7
ET-RPG 32 54 14 46.0 1.7 0 52.3
ET-MBE 44 44 12 36.6 1.7 0 61.7
Disk 90 2 8 34.9 0 0.4 64.7
Voriconazole BMD 93 7
ET-RPG 92 8 2.6 2.6 94.8
ET-MBE 93 7 1.7 2.1 96.2
Disk 94 6 0.9 1.7 97.4
a

See footnote a of Table 1 for definitions of BMD, ET-RPG, ET-MBE; disk, disk diffusion test with fluconazole (25-μg disk) and voriconazole (1-μg disk).

b

Percentage of isolates classified in the different susceptibility categories. See Materials and Methods for definitions.

c

Percentage of test results with minor, major, or very major discrepancies compared to the results of the reference BMD method at 48 h. See Materials and Methods for definitions.

d

Agreement rates reflect the percentage of isolates classified in the same category by both the agar-based (Etest and disk) and the reference BMD methods.