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Dap1p regulates sterol synthesis in yeast. Gas chromatography sterol accumulation profiles in the wild-type (RCY409-2a) (A) and dap1 (RCY409-4b) (B) strains from the same genetic cross are shown. The peaks for squalene (sq), zymosterol (zy), ergosterol (erg), lanosterol (la), and 4,4-dimethylzymosterol (dz) are indicated. Loss of Dap1p led to an increase in squalene and lanosterol and a decrease in zymosterol and ergosterol.
