FIG. 4.

hog1 and cap1Δ knockout strains behave differently, the hog1 cap1Δ double mutant having some mixed phenotypes. (A) Responses to high osmolarity and heavy metal stress of wild-type and mutant strains. Serial 10-fold dilutions of exponentially growing cells of the strains indicated were spotted onto YPD plates containing 1 M NaCl or 150 μM CdSO₄. (B) Responses to different types of oxidative stress of wild-type and mutant strains. Serial 10-fold dilutions of exponentially growing cells of the strains indicated were spotted onto YPD plates containing 5 mM H₂O₂ or 300 μM MD. (C) Catalase activities in hog1, cap1Δ, and hog1 cap1Δ mutants. The results are the means and standard deviations of three experiments.