TABLE 3.
Distribution of antibodies to HSV-1 and HSV-2 of the IgG and IgA isotypes as evidenced by type-specific ECL-WB and HSV-specific neutralizing activity in CVS lavage samples from 77 selected African women
| IgA antibody type | No. of samples with indicated IgG antibody statusa
|
Total no. of samples | ||||
|---|---|---|---|---|---|---|
| Negative | HSV-1 specific | HSV-2 specific | HSV-1 and HSV-2 specific | Not determined | ||
| Negative | 19 (1) | 8 | 4 | 3 (1) | 0 | 34 |
| HSV-1 specific | 0 | 9 | 0 | 0 | 0 | 9 |
| HSV-2 specific | 0 | 3 | 2 (2) | 2 | 0 | 7 |
| HSV-1 and HSV-2 specific | 0 | 0 | 1 (1) | 17 (7) | 0 | 18 |
| Not determined | 4 | 1 | 0 | 2 (1) | 2 | 9 |
| Total | 23 | 21 | 7 | 24 | 2 | 77 |
Numbers in parentheses represent numbers of CVS lavage samples harboring HSV-specific neutralizing activity.