FIG. 8.

Percentages of Gag-specific T cells that are CD3⁺ CD8⁺ in rhesus macaques immunized with various regimens. The adenovirus type 5 prime-adenovirus type 5 boost (Ad5-Ad5) cohort consisted of animals given two priming doses of the vector (10⁹ or 10¹¹ viral particles) followed by a booster shot of the same dose. The DNA-CRL1005 prime-adenovirus type 5 boost cohort comprised animals given three priming immunizations with 5 mg of V1Jns-gag formulated with CRL1005-based adjuvant, followed by 10⁷ viral particles of Ad5-gag. The percentage values are reported for this cohort of 11 animals before (DNA-CRL1005) and after the boost (DNA-CRL1005-Ad5). The dark diamonds and bars are the cohort arithmetic means and standard errors of the mean, respectively. These data points include those for the animals in Fig. 4 and 7.