Table 1.
Descriptive statistics for proportion inhibition (PI) and area under the receiver-operating characteristic curve (AUC) for a brucellosis c-ELISA used in 126 infected and 656 uninfected cattle and water buffalo of Trinidad incorporating multiple error structures. Median values for each statistic (eg. mean) are reported over 10,000 iterations of the Monte Carlo simulation.
Error structure | Infected | Uninfected | AUC (90% Interval)* | ||
Mean (sd) | Minimum, median, maximum | Mean (sd) | Minimum, median, maximum | ||
None (standard) | 0.812 (0.273) | 0.050, 0.983, 1.006 | 0.137 (0.091) | -0.033, 0.119, 0.752 | 0.973 |
Normal (0, 0.12) | 0.810 (0.291) | -0.033, 0.921, 1.210 | 0.130 (0.150) | -0.328, 0.129, 0.768 | 0.959 (0.945, 0.972) |
Lognormal 0.12 | 0.809 (0.285) | -0.136, 0.983, 1.006 | 0.118 (0.207) | -0.685, 0.137, 0.752 | 0.952 (0.934, 0.968) |
Normal (0.1, 0.12) | 0.753 (0.271) | -0.031, 0.856, 1.123 | 0.122 (0.139) | -0.301, 0.120, 0.714 | 0.959 (0.944, 0.972) |
Normal (-0.1, 0.12) | 0.877 (0.315) | -0.036, 0.996, 1.316 | 0.140 (0.162) | -0.361, 0.139, 0.829 | 0.959 (0.945, 0.972) |
Normal (0, 0.24) | 0.806 (0.344) | -0.273, 0.880, 1.459 | 0.108 (0.266) | -0.906, 0.133, 0.877 | 0.933 (0.907, 0.953) |
Lognormal 0.24 | 0.800 (0.320) | -0.542, 0.982, 1.006 | 0.059 (0.419) | -2.074, 0.143, 0.785 | 0.928 (0.899, 0.950) |
*Interval formed as the 5th and 95th percentiles of Monte Carlo simulations
sd = standard deviation