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. 2006 Aug 18;2(8):e131. doi: 10.1371/journal.pgen.0020131

Figure 1. Pathways of IFNG-Induced GAF-Mediated Immunity and IFNA-Induced ISGF3-Mediated Immunity.

Figure 1

Patients homozygous for null STAT1 mutations [36,37] suffer from both mycobacterial and viral diseases. Patients heterozygous for STAT1 mutations L706S, Q463H, and E320Q suffer from mycobacterial but not viral diseases ([17] and this report).