Figure 3.

Effects of chemotherapy and immunotherapy on HeLa-luc cell growth in vivo. HeLa-luc cells were injected into the peritoneal cavity (time 0) at 1x10⁴ cells per animal. Groups of animals were either not treated (n=7), or treated with cis-platinum (n=6) or CIK cells at an effector to target ratio of 1000:1 (n=7). Tumor cell growth, as indicated by transmission of bioluminescent light, was assessed at weekly intervals and plotted for each animal with respect to time. The range of tumor cell growth in the untreated control animals is represented by the gray area.