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Macroscopic observation of primary and metastatic tumor nodules in the lungs of athymic nude mice after orthotopic implantation of PC-14, A549 and Lu-99 cells. PC-14, A549 or Lu-99 cells were implanted into the lungs of KSN mice as described in Figure 1. Autopsy was performed on day 56 after the implantation and the primary (open arrowheads) and metastatic (closed arrowheads) tumor nodules of each cell line had been observed.
