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. 2006 Aug 15;398(Pt 2):169–176. doi: 10.1042/BJ20060303

Figure 1. Genomic structure of the hCLS1 gene and sequence comparison with yeast CLS1.

Figure 1

The hCLS1 gene consists of seven exons (A) that are mapped to chromosome 20p13-p12.3. The coding region is indicated by solid bars, whereas the 3′-untranslated region is marked by an open box. The predicted hCLS1 protein sequence shares extensive homology with the yeast CLS1 (shaded regions) (B), and carries a sequence motif [D(X)2DG(X) 2AR(X)8–9G(X)3D(X)3D] (underlined) conserved among members of the CLS family from yeast to plants.