Table 1. Comparison of some pharmaceutical functions of the toxins.
Cytotoxicity (IC50, μg/ml) | ||||
---|---|---|---|---|
Toxin | LD50 (mg/kg) | Patch clamp (IC50, μM) | HUVEC | L929 cells |
rLNTX1 | 0.5114 | 0.763 | 1.58 | 0.31 |
Oh-4 | 0.25* | − | − | − |
rLNTX3 | 0.4150 | 0.385 | 0.84 | 0.30 |
Oh-6A/6B | 0.17/0.14* | − | − | − |
Crude venom | − | − | 4.2 | 1.8 |
Cobrotoxin | − | − | >58 | >58 |
* Data from [26].