Figure 3.

Microvessel density counting of mouse tumors. The chart in (A) shows a trend for TM-treated tumors to have decreased microvessel density counts. The difference is not statistically significant as demonstrated by the overlapping standard deviation error bars. In (B) the average microvessel density counts for untreated, RT-treated, TM-treated, and RT+TM-treated tumors show not statistically significant differences. Each bar represents the average microvessel counts at 200x magnification from three mice (with two to five hot spots counted per mouse tumor), and with two independent investigators counting. The same results occur for when the data for each investigator are analyzed separately (data not shown).