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. Author manuscript; available in PMC: 2007 Apr 1.
Published in final edited form as: Am J Physiol Heart Circ Physiol. 2005 Nov 18;290(4):H1642–H1650. doi: 10.1152/ajpheart.00586.2005

Fig. 4.

Fig. 4

Burn injury treated with IS followed by septic challenge on postburn day 7 significantly reduced left ventricular developed pressure (LVP), maximal rate of LVP rise (+dP/dtmax), and maximal rate of LVP fall (−dP/dtmax) responses to either increases in left ventricular volume (A) or increases in perfusate calcium (B) compared with values generated by hearts from sham-burned animals. HSD administration in burned animals attenuated sepsis-related myocardial contractile defects. All values are means ± SE. *Significant differences from sham burn (P < 0.05, ANOVA and Student-Newman-Keuls); +significant differences in burn + HSD + sepsis compared with burn + IS followed by septic challenge (P < 0.05, ANOVA and Student-Newman-Keuls).