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. Author manuscript; available in PMC: 2006 Aug 17.
Published in final edited form as: J Pediatr. 2006 Jan;148(1):23–29. doi: 10.1016/j.jpeds.2005.08.075

Table III, B.

Modeling of changes in BMI z-score with octreotide therapy in 24 patients with hypothalamic obesity

Parameter ΔBMI z-score in 4 months 95% CI P
Baseline (CIRgp 1, CISI 1, female, pubertal) − 0.23 − 0.47, 0.00 .052
Modifications to the above effects
 For every doubling of CIRgp (secretion) +0.19 +0.01, +0.37 .036
 For every doubling of CISI (sensitivity) + 0.07 − 0.09, +0.23 .35
 CIRgp × CISI interaction − 0.13 − 0.27, 0.00 .051
 Male sex +0.10 0.01, +0.20 .067
 Prepubertal or no sex hormone 0.00 − 0.12, +0.12 .99