Table 1.
MEAN FOLD-CHANGE (LOG10 RQ) | CHROMOSOME LOCALIZATION | PUTATIVE TARGETS ASSOCIATED WITH COLORECTAL CARCINOGENESIS | |
hsa-miR-147 | -4.56 | 9q32.3 | |
hsa-miR-127 | -4.27 | 14q32.31 | |
hsa-miR-145 | -4.13 | 5q32 | TGFRII, APC |
hsa-miR-370 | -4.05 | 14q32.31 | BAX, AKT1 |
hsa-miR-299 | -3.90 | 14q32.31 | B-CATENIN, CDKN1A |
hsa-miR-199a | -3.80 | 1q24.3 | |
hsa-miR-154* | -3.71 | 14q32.31 | MLH1 |
hsa-miR-199-s | -3.64 | 19p13.2 | |
hsa-miR-323 | -3.56 | 14q32.31 | MSH2 |
hsa-miR-154 | -3.55 | 14q32.31 | |
hsa-miR-134 | -3.34 | 14q32.31 | |
hsa-miR-342 | -3.15 | 14q32.2 | |
hsa-miR-199a* | -3.06 | 1q24.3 | |
hsa-miR-137 | -3.05 | 1p21.3 | TGFRII |
hsa-miR-368 | -3.03 | 14q32.31 | |
hsa-miR-130a | - 3.02 | 11q12.1 | TGFRII |
hsa-miR-214 | -2.36 | 1q24.3 | TP53, B-CATENIN, TGFRII, BAX, CDKN2B, EGFR |
hsa-miR-337 | - 2.25 | 14q32.31 | CDKN2A |
hsa-miR-125b | -2.20 | 11q24.1 | VEGF, IGFRI, VEGFR |
hsa-miR-199b | -2.19 | 9q34.11 | |
hsa-miR-133a | -2.11 | 18q11.2 | BAX, K-RAS |
hsa-miR-26b | -1.82 | 2q35 | APC |
hsa-miR-133b | -1.66 | K-RAS | |
hsa-miR-296 | -1.61 | 20q13.32 | |
hsa-miR-124b | 1.42 | MLH1 | |
hsa-miR-338 | 1.63 | 17q25.3 | |
hsa-miR-9* | 1.68 | 5q14.3 | TCF4, MSH2 |
hsa-let-7g | 1.73 | 3p21.2 | TGFRII |
hsa-miR-372 | 1.76 | 19q13.42 | TGFRII, SMAD2, MLH1, AKT1 |
hsa-miR-182* | 1.77 | ||
hsa-miR-219 | 1.93 | 6p21.32 | TGFRII |
hsa-miR-205 | 2.21 | 1q32.2 | K-RAS, SMAD4, MSH2, PTEN |
hsa-miR-194 | 2.23 | 1q41 | |
hsa-miR-142-3p | 2.29 | APC | |
hsa-miR-135a | 2.36 | 3p21.2 | MSH2 |
hsa-miR-215 | 2.42 | 1q41 | IGFRI |
hsa-miR-142-5p | 2.51 | 17q23.2 | |
hsa-miR-135b | 2.90 | 1q32.1 | MSH2 |
hsa-miR-141 | 3.28 | 12p13.31 | APC, MSH2 |
hsa-miR-182 | 3.41 | 7q32.2 | IGFRI |
hsa-miR-200b | 3.44 | 1p36.33 | MLH1 |
hsa-miR-200c | 3.64 | 12p13.31 | MLH1, SMAD2 |
hsa-miR-96 | 3.64 | 7q32.2 | K-RAS |
hsa-miR-200a | 3.73 | 1p36.33 | MSH2 |
hsa-miR-203 | 3.77 | 14q32.33 |