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. 2003 May 15;111(10):1475–1486. doi: 10.1172/JCI17295

Figure 6.

Figure 6

Inhibition of p38 enhances the activity of an NFAT-dependent luciferase reporter transgene in vivo. (a) Schematic representation of the 9×NFAT-TATA-luciferase construct used to generate transgenic mice. (b) Relative luciferase (luc) levels from cardiac protein extracts from 3-week-, 2-month-, or 4-month-old nontransgenic mice (background), NFAT-luc transgenic mice, or double transgenic mice containing NFAT-luc and dnp38α. All data are shown relative to background (no transgene), which was set to a value of 1. (*P < 0.05 versus NFAT-luc alone).