TABLE 3.
Immunization or antibodya | Neutralization titerb against:
|
||
---|---|---|---|
VSV | VSVΔG-89.6G-GFP | VSVΔG-89.6G(4-7)-GFP | |
rwt VSV | 1:10,240 | 0 | 0 |
VSV-HA | 1:10,240 | 0 | 0 |
VSV-89.6G | 1:5,120 | 1:40-1:80 | 1:160 |
VSV-89.6G(4-7) | 1:10,240 | 1:20 | 1:160 |
VSV-89.6G(2-7) | 1:10,240 | 0 | 1:20-1:40 |
HIV Ig | 0 | 1:800 | 1:800 |
Mice were immunized with the indicated viruses. Pooled immunoglobulin from HIV-infected patients (HIV Ig) was used as a control in the last line.
Titers of neutralizing antibodies in sera of immunized mice.