Skip to main content
. 2002 May;76(9):4162–4171. doi: 10.1128/JVI.76.9.4162-4171.2002

FIG. 5.

FIG. 5.

Bcl-2 overexpression and pancaspase inhibitor attenuate CHOP expression induced by JEV infection. (A) Kinetics of CHOP induction followed by JEV infection in parental BHK-21 or in B2-5, a bcl-2-overexpressing BHK-21 cell line, were determined by Western immunoblotting as described in the legend to Fig. 4. (B) JEV-mediated CHOP induction was delayed by treatment of BHK-21 cells with a pancaspase inhibitor, z-VAD-fmk. JEV-infected BHK-21 cells were treated with either dimethyl sulfoxide (upper panel) or 50 μM z-VAD-fmk (lower panel) for the indicated periods postinfection. M, mock- infected cells.