TABLE 1.
RSV titers following primary infection of CD1d−/− mice
| Strain | Day p.i. | RSV titer ina:
|
|
|---|---|---|---|
| CD1d+/+ mice | CD1d−/− mice | ||
| 129×B6 | 4 | 4.68 ± 0.97 | 4.72 ± 1.71 |
| 7 | 2.70 ± 1.33 | 4.72 ± 1.19b | |
| B6 | 4 | 4.79 ± 0.65 | 5.61 ± 0.38 |
| 7 | 3.92 ± 0.98 | 4.86 ± 1.40b | |
| BALB/c | 4 | 6.68 ± 0.53 | 6.72 ± 0.48 |
| 7 | 2.79 ± 0.62 | 2.32 ± 0.71 | |
a
Data are presented as means ± SEMs of the log10(PFU/gram of lung); n = 15 for 129×B6 mice (three experiments combined), n = 8 for B6 mice (two experiments combined), and n = 18 for BALB/c mice (four experiments combined).
b
Statistically significant difference (P < 0.05 relative to CD1d+/+ mice of the same strain).