Table 7.

Sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio and negative likelihood ratio of inflammatory markers in diagnosing sepsis

Variable	Cut-off level	Sensitivity (%)	Specificity (%)	Positive predictive value (%)	Negative predictive value (%)	Positive likelihood ratio	Negative likelihood ratio
Procalcitonin	0.087 ng/ml	79.7	42.1	84.3	34.8	1.4	0.48
	0.1 ng/ml	75.7	52.6	86.2	35.7	1.6	0.46
	0.25 ng/ml	55.0	89.5	95.4	34.0	5.2	0.5
	0.5 ng/ml	45.9	89.5	94.4	29.8	4.4	0.6
Lipopolysaccharide-binding protein	20 μg/ml	81.0	68.4	90.9	48.2	2.6	0.28
	40 μg/ml	41.9	100.0	100.0	30.7		0.58
C-reactive protein	38 mg/l	79.7	57.9	88.1	42.3	1.9	0.35
	50 mg/l	71.6	63.2	88.3	36.4	1.9	0.45
	100 mg/l	63.5	94.7	97.9	40.0	11.9	0.39
IL-6	25 pg/ml	81.1	78.9	93.8	51.7	3.8	0.24
	50 pg/ml	70.3	89.5	96.3	43.6	6.7	0.33