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. 1999 Feb 16;96(4):1541–1546. doi: 10.1073/pnas.96.4.1541

Figure 3.

Figure 3

Promoter activity of 5′ sequences from the human IL-16 gene in Jurkat T cells and HeLa cells. The numbers below indicate the sequences of DNA fragments cloned in front of a luciferase reporter gene. The activity of a pGL3 vector (Promega) containing the SV40 early promoter is also shown. (A) Deletion analysis of the 5′ IL-16 DNA. Relative luciferase activities are given as fold activity above the activity of the promoter-less pGL3-Basic vector. The standard deviations represent the mean values from four independent experiments. (B) TPA-mediated induction of 5′ segments of IL-16 gene. Differences of luciferase activities are shown between uninduced cells and cells treated with 10 nM TPA and indicated as “Fold activation.” The standard deviations represent the mean values from three independent experiments.