FIG. 2.

Change in temperatures of ferrets infected with H5N1 viruses. Ferrets were infected with 10⁷ EID₅₀ of either HK/483 or HK/486. Temperatures were assessed twice daily, beginning 3 days prior to infection and for 14 days after infection. The numbers of animals monitored each day were as follows: days −3 to 1, n = 9; days 2 and 3, n = 7; days 4 and 5, n = 5; and days 7 to 14, n = 3. The means of preinfection temperatures (days −3 to −1) were subtracted from the individual p.i. temperatures to obtain temperature changes in individual ferrets. The mean change in temperature for all ferrets in a group is shown. Three ferrets inoculated with each virus were sampled on remaining days. The mean temperature change in six mock-infected control ferrets ranged from −0.5 to +0.4°C.