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. Author manuscript; available in PMC: 2006 Aug 21.

Published in final edited form as: AIDS Res Hum Retroviruses. 2004 Nov;20(11):1259–1268. doi: 10.1089/0889222042545063

Table 1.

Binding of Monoclonal Antibodies to gp120 ± mC3d₃

	Monoclonal antibody
Samples	F105	1b12	2F5	48d	17b
R2
wt gp120	25,000^a	25,000	<10	50,000	25,000
wt gp120–mC3d₃	25,000	25,000	<10	12,500	12,500
wt gp120 + sCD4	50,000	12,500	<10	50,000	25,000
wt gp120–mC3d₃ + sCD4	25,000	50,000	<10	25,000	50,000
ADA
wt gp120	25,000	25,000	<10	1,600	800
wt gp120–mC3d₃	25,000	25,000	<10	400	400
wt gp120 + sCD4	50,000	25,000	<10	25,000	25,000
wt gp120–mC3d₃ + sCD4	50,000	50,000	<10	25,000	25,000
ADA (PM)
wt gp120	50,000	25,000	<10	25,000	25,000
wt gp120–mC3d₃	25,000	25,000	<10	12,500	25,000
wt gp120 + sCD4	25,000	25,000	<10	25,000	25,000
wt gp120–mC3d₃ + sCD4	50,000	25,000	<10	25,000	25,000
89.6
wt gp120	25,000	25,000	<10	3,200	400
wt gp120–mC3d₃	25,000	25,000	<10	400	400
wt gp120 + sCD4	50,000	25,000	<10	25,000	50,000
wt gp120–mC3d₃ + sCD4	50,000	25,000	<10	50,000	50,000
89.6 (PM)
wt gp120	25,000	25,000	<10	25,000	25,000
wt gp120–mC3d₃	25,000	25,000	<10	25,000	25,000
wt gp120 + sCD4	25,000	25,000	<10	25,000	25,000
wt gp120–mC3d₃ + sCD4	25,000	25,000	<10	50,000	50,000

^a

Value represents the inverse of the endpoint dilution titer