FIG. 1.
The F gene ORF and the amino-terminal 170 residues of the CDV F protein. (Top) Schematic drawing of the F gene. The predicted reading frame beginning with the first in-frame AUG is boxed. Hydrophobic regions are hatched. (Center) Comparison of the amino acid sequence of the CDV strains Onderstepoort (OS and OL, small- and large-plaque-forming variants), Rockborn (Rb), Snyder Hill (SH), and 5804Han89 (5804) starting from the first in-frame translation initiation codon in the F ORF. (Bottom) Predicted hydrophilicity and structural organization of the first 170 residues of CDVOS. n and h, N-terminal and hydrophobic subdomains. The cleavage site between position 135 and 136 (A↓QIHW) was predicted by the method of Ladunga et al. (11).