FIG. 10.

IF localization of β-COP in HeLa cells infected with MVA at 4 h 30 min postinfection. HeLa cells grown on coverslips were infected (d to f) or mock infected (a to c) with MVA at an MOI of 10 and fixed at 4 h 30 min after infection. Fixed cells were triple labeled with DAPI (a and d), anti-β-COP (b and e), and anti-p16 (c and f). The large arrows indicate viral DNA replication sites, and the small arrows indicate p16-labeled structures. In panel e the small arrows indicate p16 structures that are adjacent to COP-labeled structures.