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. 1999 Feb 16;96(4):1553–1558. doi: 10.1073/pnas.96.4.1553

Figure 4.

Figure 4

Pharmacokinetics of serum hIFN-ω after a single i.m. injection of hIFN-ω pDNA. C57BL/6 mice received a single i.m. injection of 100 μg of hIFN-ω pDNA. Serum was collected every 2–3 days for 2 weeks after pDNA injection, and samples were analyzed in an ELISA specific for hIFN-ω. Each data point represents the mean hIFN-ω serum level of four mice. Peak serum levels of 254 pg/ml were found on day 6 after a pDNA injection, and expression continued to day 14, the last time point of the study. Mice injected with the control pDNA were negative in the IFN-ω ELISA.