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. Author manuscript; available in PMC: 2006 Aug 22.
Published in final edited form as: J Biol Chem. 2006 May 4;281(30):21332–21344. doi: 10.1074/jbc.M603814200

FIGURE 6. Effects of mutations of hydrophobic residues in the IIS4 segment on sodium channel activation.

FIGURE 6

a– d, voltage dependence of activation for wild-type Nav1.2, and the indicated mutant channels is shown. Conductance-voltage relationships were determined as described under “Experimental Procedures.”