Phosphorus-31 solid-state 3D projection
reconstruction MR image of a section of the metaphyseal portion of
porcine tibia containing a small capsule of synthetic hydroxyapatite
powder to simulate a calcium phosphate-based prosthetic implant. The
hydroxyapatite and the bone mineral, although chemically highly similar
calcium phosphates, exhibit different MR spin lattice relaxation times
T1. Two raw MR images, each with a different
T1 sensitivity, were obtained and then
appropriately combined on a pixel-by-pixel basis to yield chemically
pure images of each material. The two images were then separately
colorized and overlaid to produce the composite image. MR is unique
among all 3D imaging methods applicable to solid materials, such as
bone, ceramics, and polymers, because of its great sensitivity to
chemical composition.