TABLE 1.
Hematology and clinical biochemistry of ES and control mice
| Parameter | Value for:
|
Pa | |||
|---|---|---|---|---|---|
| Controls
|
ES mice
|
||||
| Mean | SD | Mean | SD | ||
| Metabolites | |||||
| Glucose (mmol/liter) | 7.84 | 2.13 | 9.86 | 1.78 | 0.17 |
| Albumin (g/liter) | 25.8 | 1.30 | 26.2 | 1.64 | 0.91 |
| Cholesterin (mmol/liter) | 2.4 | 0.12 | 2.6 | 0.19 | 0.08 |
| Triglycerides (mmol/liter) | 1.46 | 0.39 | 1.5 | 0.65 | 0.75 |
| Enzymes | |||||
| Alkaline phosphatase (U/liter) | 130.2 | 10.4 | 122.4 | 13.2 | 0.47 |
| Aspartate amino transferase (U/liter) | 68.8 | 2.9 | 62.8 | 15.9 | 0.92 |
| Alanine amino transferase (U/liter) | 39.2 | 16.6 | 42.8 | 10.4 | 0.60 |
| Electrolytes | |||||
| Ca2+ (mmol/liter) | 2.4 | 0.05 | 2.45 | 0.07 | 0.25 |
| Mg (mmol/liter) | 1.41 | 0.09 | 1.37 | 0.09 | 0.21 |
| Fe (μmol/liter) | 31.6 | 2.5 | 33.9 | 2.1 | 0.25 |
| Phosphorus (mmol/liter) | 2.65 | 0.19 | 2.71 | 0.17 | 0.56 |
| Na (mmol/liter) | 167.6 | 3.9 | 16.7 | 1.6 | 0.83 |
| K (mmol/liter) | 4.78 | 0.40 | 4.96 | 0.59 | 0.60 |
| Cl (mmol/liter) | 122.8 | 2.8 | 122.8 | 2.0 | 0.83 |
| Erythrocytes | |||||
| Hematocrit (%) | 47.2 | 1.4 | 49.6 | 1.1 | 0.03 |
| Hemoglobin (g/dl) | 15.6 | 0.5 | 16.2 | 0.3 | 0.02 |
| Erythrocytes (106/μl) | 9.8 | 0.39 | 10.6 | 0.3 | 0.01 |
| Mean corpuscular hemoglobin (pg) | 1.6 | 0 | 15.2 | 0.5 | 0.04 |
| Mean corpuscular hemoglobin content (g/dl) | 33.2 | 0.5 | 32.8 | 0.5 | 0.35 |
| Mean corpuscular volume (fl) | 4.8 | 0.7 | 46.8 | 0.8 | 0.60 |
| Leukocytes | |||||
| Leukocytes (103/μl) | 4.1 | 0.8 | 5 | 0.8 | 0.08 |
| Neutrophils/μl | 1,410 | 2,060 | 70.2 | 15.8 | 0.25 |
| Eosinophils/μl | 9.4 | 5.2 | 8.1 | 3.1 | 0.34 |
| Basophils/μl | 24 | 23 | 2.8 | 26 | >0.99 |
| Monocytes/μl | 5.6 | 5.1 | 10.8 | 7.9 | 0.34 |
| Lymphocytes/μl | 3,424 | 81.5 | 4,073 | 69.0 | 0.60 |
a
P values were calculated by using the Mann-Whitney U test; the level of significance was set at a P value of ≤0.05.