. 2002 Jan;12(1):88–97. doi: 10.1101/gr.206002

Table 3.

Effects of the Mom1 and Mom2 Loci on the Incidence of Colon Polyps in N2 Offspring from the B6 × D2B6F1 Apc^Min and D2 × D2B6F1 Apc^Min Backcrosses^a

Genotypes of B6 × D2B6F1 Apc^Min N2 offspring	*Mom1*^S/Mom1^S	*Mom1*^R/Mom1^S	p values

Mom2⁺/Mom2⁺	71.4% (5/7)	37.5% (3/8)	p = 0.3147
Mom2^R/Mom2⁺	8.6% (3/35)	3.4% (1/29)	p = 0.6198
p values	p = 0.0012	p = 0.0256

Genotypes of D2 × D2B6F1 Apc^Min N2 offspring	*Mom1*^R/Mom1^S	*Mom1*^R/Mom1^R	Total

Mom2⁺/Mom2⁺	66.7% (2/3)	50.0% (1/2)	60.0% (3/5)
Mom2^R/Mom2⁺	0.0% (0/9)	14.2% (1/7)	6.3% (1/16)
p value			p = 0.0276

^aN2 progeny of D2B6F1 Apc^Min parents #5, #6, and #7 from Table 1 were classified according to strain background as well as genotype and phenotype at the Mom1 and Mom2 loci, respectively. The % of mice within each class is given. The numbers in parentheses show the actual number of mice with ≥1 colon polyp over the total number of mice in each class. P values were determined by the Fisher's exact test.