Figure 7.

This figure indicates how DomainFinder's cautious assignment of consensus regions can produce consensus regions that the DRange protocol considers to be noise. In this instance, several S95 rep hits have hit a region of a gene (indicated in black). The DomainFinder algorithm has attempted to merge these into a consensus region but one of them is considered by DomainFinder to be too small to belong with the others (it has insufficient overlap with the others), and a second consensus, made from only one Srep hit, is built. For the purposes of the Gene3D resource, it is sufficient that the smaller domain is merged into the larger region.