Figure 6.
Colocalization of ATR and phosphorylated Rad17 in UV-induced nuclear foci. (A) HeLa cells were untreated or treated with 50 J/m2 of UV. After 4 h, the cells were immunostained with antibodies to ATR and p-Ser635 of Rad17. (B) HeLa cells transfected with siRNA targeting Rad17 or control siRNA were untreated or treated with UV as in A. After 4 h, the cells were immunostained with antibodies to ATR.