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. 2002 Feb 1;16(3):295–300. doi: 10.1101/gad.960702

Figure 2.

Figure 2

Induction of the pTa enhancer by NICD. Cell line 293 was transfected with reporter constructs together with the NICD expression vector. Normalized reporter activities in the presence of NICD or of an empty expression vector were determined, and their ratio is presented as fold induction by NICD. The results represent the mean + SD of three independent experiments. Reporter constructs contained the indicated enhancer fragments upstream of the mouse pTa promoter (pTa) or of the SV40 promoter TATA box (TATA). The mouse (mpTa) or human (hpTa) pTa enhancers were either wild-type or harbored the mutations shown in Figure 1A (mpTa mut., hpTa mut.).