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. 2006 Jul 20;1:22. doi: 10.1186/1748-717X-1-22

Table 1.

Overview of dose-volume histograms with proton, IMRT and photon conventional planning for the PTV and OARs in the proton-photon planning comparison literature

PTV/OARs Series (ref. no.) V95% Protons (mean) V95% IMRT (mean) V95% Photons (mean) Mean Dose (%) Protons Mean Dose (%) IMRT Mean Dose (%) Photons
PTV (breast only)
Lomax et al. [33] 97.1 92.2 86.6
Johansson et al. [34] 94.0 85.9 88.8
Fogliata et al. [38] 99.8 95.5 92.2
Heart
Lomax et al. [33] 11.6 24.0 29.3
Johansson et al. [34] 21.0* 41.0* 61.0*
Fogliata et al. [38] 4.4 5.6 5.0
Lung (ipsilateral)
Lomax et al. [33] 25.0 33.0 33.3
Johansson et al. [34] 1.0* 18.0* 29.0*
Fogliata et al. [38] 7.0 17.1 22.5

IMRT, intensity modulated radiotherapy; PTV, planning target volume; OAR, organ at risk; V95%, volume (in percentage) receiving 95% of the prescribed dose.

*estimated % of the prescribed dose from the dose-volume histograms administered to the heart and lung