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. 2002 Mar 1;16(5):594–607. doi: 10.1101/gad.939502

Figure 2.

Figure 2

PKCI-r identity. (A) DNA and deduced amino acid sequence of PKCI-r. The 652-bp PKCI-r cDNA contains a 390-bp open reading frame that encodes a 130-amino-acid protein. The termination codon (*), putative polyadenylation sequence (bold at position 607), and boundaries of exons (vertical arrows) are indicated. The sequences of the primers used for PCR are underlined. The purine-rich region bound by ASF/SF2 (position 573–589) is boxed. (B) Amino acid sequence comparison of PKCI-r with PKCI-1 family members. Dark shaded regions indicate conserved residues in most family members. Light shaded regions indicate partial amino acid homology with any other family member. Arrows show the three conserved histidyl residues that unify the HIT superfamily. The PKCI-1 sequences used for this alignment include Bos taurus (GenBank database accession no. A35350), Oryctolagus cuniculus (Y11175), Mus musculus (U60001), Homo sapiens (U27143), Gallus gallus (AI982310), and Gallus gallus PKCI-r.