Abstract
Circulating lymphocytes of a normal boy were unequivocally stimulated by irradiated leukaemic lymphoblasts from his identical twin with acute lymphoblastic leukaemia. This reaction indicates that there is an `antigenic' disparity between these two types of cells. It is possible that leukaemic cells may acquire new surface antigens or that existing surface antigens of lymphoid cells may be modified during the process of leukaemogenesis.
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Selected References
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