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. 2000 Feb 1;97(3):1190–1195. doi: 10.1073/pnas.97.3.1190

Figure 1.

Figure 1

Alignment of IL-18BP isoforms amino acids. (A) Four human isoforms, IL-18BPa, IL-18BPc, IL-18BPd, and IL-18BPb, are depicted. * above the asparagine residues (nos. 77, 101, and 145) locate glycosylation sites. The inverted carets indicate arrest sites of the amino acid sequence resulting from mRNA splicing followed by the amino acid sequence encoded by the new ORF. The Ig domain is indicated in green. The color blue represents identical amino acids in the new ORF of inactive isoforms. The color red represents closely related carboxyl termini of active isoforms. The color yellow represents a potential binding motif. (B) Mouse IL-18BPc and IL-18BPd isoforms are shown. The colors represent similar indications as shown for human IL-18BP isoforms.