Table 2.
IL-11Rα immunostaining in cynomolgus and rhesus monkey implantation sites, and human first trimester decidua and placenta.
| Implantation sites | ||||||
| Cynomolgus | Rhesus | Human | ||||
| Day of gestation | 12–14 | 17 | 27–49 | 74–150 | 24–35 | 8–9 weeks |
| Trophoblast | ||||||
| Villi – cyto | - | -/+ | - | - | ++/+ | +++ |
| - syncytio | - | -/+ | - | - | ++/+ | +++ |
| - mesenchyme | -/+ | - | ++/+ | + | + | +++ |
| Shell | + | + | -/+ | + | - | N/A |
| Cyto- invading artery | + | +/++ | -/+ | - | - | N/A |
| Mother | ||||||
| Decidua | ++ | +++ | +++ | +++ | +++ | +++ |
| VSM | -/+ | +++ | +++ | + | + | ++ |
| Endothelial | -/+ | +++ | +/++ | + | - | -/+ |
| Glands | - | -/+ | -/+ | - | -/+ | + |
| Perivascular | - | ++/+ | ++/+ | + | +++ | ++ |
| Epithelial plaques | +/++ | + | N/A | N/A | N/A | N/A |
Relative staining intensities are represented as: – (no staining), + (low), ++ (moderate) and +++ (high). Trophoblast cellular compartments include: Chorionic villi (villi), villous cytotrophoblast (cyto), villous syncytiotrophoblast (syncytio), villous stromal mesenchyme (mesenchyme), cytotrophoblast shell (shell), cytotrophoblast invading spiral artery (cyto-invading artery). Maternal cellular compartments include: decidua, vascular smooth muscle cells (VSM), endothelial cells, glands, perivascular cells and epithelial plaque.