Figure 5.

External and internal images of liver lesions of AC3488-GFP. (A) Lateral, whole-body image of metastatic liver lesions of a GFP-expressing human colon cancer in the left (thick arrow) and right lobes (fine arrow) of a live nude mouse at day 21 after surgical orthotopic transplantation. (B) Cross-section of mouse shown in A corresponding to the level of the external image of the tumor in the liver that was acquired (A). Fine arrows show metastatic lesions in the right lobe of liver, and the thick arrow shows the metastatic lesion in the left lobe of liver. (C) Fluorescent whole-body ventral image of primary colon tumor (arrow). (D) Dorsal external image of metastatic tumor in the caudal region of the left and right lobes of the liver (thick arrows) and skull metastasis (arrowheads).