MFBs in the
ZnT3−/− hippocampus show normal
ultrastructure. Electron micrographs of MFBs in s lucidum of CA3, taken
from a ZnT3+/+ (A) and a
ZnT3−/− (B) mouse.
ZnT3−/− MFBs were normal with respect
to their size, the approximate number of small, clear synaptic vesicles
contained within them, the numbers and types of synaptic contacts made
with dendritic spines, and the presence of mitochondria. Note the
asymmetric synaptic contacts (arrowheads) on dendritic spines (S) and a
pyramidal cell dendrite (D).