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Invasiveness of wild-type (wt) L. monocytogenes, the Δiap mutant, and the iap+ revertant. Caco-2 epithelial cells (A) or 3T6 mouse fibroblasts (B) were infected for 1 h at an MOI of 5, and intracellular bacteria (grown to the late-exponential-growth phase) were quantified by determining the CFU per well. Each column represents the mean of one representative experiment performed in triplicate. Error bars, standard deviations.
