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Effect of the −656 SERPINH1 SNP on promoter activity. SERPINH1 promoter fragments representing the −656 C and T alleles were cloned into the pGL3 basic vector. The relative Photinus luciferase activities ± SE (n = 3 separate experiments performed with triplicate wells for each cell host) standardized to Renilla luciferase were compared by using the Tukey–Kramer test. Values with different letters are significantly different (P < 0.05) from each other within each cell host.
