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Effect of exogenous LTD4 challenge on salbutamol-induced cAMP accumulation in HASMC. Effect of LTD4 (10-6M) challenge on cAMP accumulation induced by 10-4M salbutamol in HASMC. Note the weaker effect of salbutamol compare to isoproterenol (10-5 M) and the similarity with the effects of LTD4 in Fig.s 1-3. The results are presented as mean ± s.e.m. of two experiments performed in triplicate. *P < 0.01 (one-way ANOVA).
