Table 1.
Proteins that are uniquely present in most epsilon proteobacteria (Campylobacterales)
| Wolinella Genome ID No. | Accession Number | Length | Possible/Predicted Function | Comments |
| WS0030 | NP_906303.1 | 68 aa | Probable periplasmic protein, tat-domain | All significant hits from ε-Proteobacteria |
| WS0086 | NP_906354 | 181 aa | Putative helicase, gnl|CDD|14084, COG4951 | All significant hits from ε-Proteobacteria |
| WS0133 | NP_906397 | 397 aa | Putative integral membrane protein | All significant hits from ε-Proteobacteria |
| WS0134 | NP_906398.1 | 214 aa | Conserved hypothetical protein | All significant hits from ε-Proteobacteria |
| WS0154 | NP_906417.1 | 336 aa | Probable membrane protein | All significant hits from ε-Proteobacteria |
| WS0159 | NP_906422 | 203 aa | Conserved hypothetical protein, unknown function | All significant hits from ε-Proteobacteria |
| WS0169 | NP_906432 | 92 aa | Possible membrane protein (corresponds to Cj0692c and HP0748) | All significant hits from ε-Proteobacteria |
| WS0172 | NP_906435 | 675 aa | Putative membrane protein, similar to HP0358 | All significant hits from ε-Proteobacteria |
| WS0180 | NP_906442 | 74 aa | Related to Cbb3-type cytochrome oxidase, subunit 3, gnl|CDD|13876, COG4736 | All significant hits from ε-Proteobacteria |
| WS0184 | NP_906445.1 | 205 aa | Probable membrane protein | All significant hits from ε-Proteobacteria |
| WS0185 | NP_906446 | 163 aa | Related to FixH protein, gnl|CDD|23975 | All significant hits from ε-Proteobacteria |
| WS0216 | NP_906474 | 330 aa | Conserved hypothetical protein, unknown function | All significant hits from ε-Proteo; E value for C. upsaliensis is higher than the threshold. |
| WS0260 | NP_906515.1 | 142 aa | Conserved hypothetical protein, unknown function | All significant hits from ε-Proteobacteria; E value for C. lari is above the threshold. |
| WS0266 | NP_906520 | 271 aa | Conserved protein, H. pylori homolog may be related to the plasminogen binding protein pgbA. | All significant hits from ε-Proteobacteria; Jonsson et al. (2004) |
| WS0316 | NP_906567 | 163 aa | Conserved protein related to the RDD family; gnl|CDD|25144, pfam06271 | Besides ε-Proteo, three other hits were below the threshold value; Large jump in E value from last ε-Proteo (6E-15) to the first of these hits (.003). |
| WS0447 | NP_906689 | 328 aa | Putative membrane protein, corresponds to antigen P44Hh9 of H. hepaticus. | All significant hits from ε-Proteobacteria |
| WS0448 | NP_906690 | 276 aa | Probable periplasmic protein | All significant hits from ε-Proteobacteria |
| WS0476 | NP_906716 | 77 aa | NuoE, Putative NADH Oxidoreductase I | All significant hits from ε-Proteobacteria |
| WS0480 | NP_906720 | 428 aa | Putative NADH Oxidoreductase I | All significant hits from ε-Proteobacteria |
| WS0490 | NP_906728 | 778 aa | Flagellar functional protein, Pf1a | All significant hits from ε-Proteobacteria |
| WS0520 | NP_906757.1 | 247 aa | TonB domain protein | All significant hits from ε-Proteobacteria |
| WS0563 | NP_906797 | 164 aa | Putative integral membrane protein; identified by similarity to PIR:B71953 | All significant hits from ε-Proteobacteria |
| WS0575 | NP_906809 | 217 aa | Putative lipoprotein, The C. lari homolog is a secreted protein involved in flagellar motility. | All significant hits from ε-Proteobacteria. |
| WS0604 | NP_906835 | 390 aa | Probable periplasmic protein | All significant hits from ε-Proteobacteria |
| WS0802 | NP_907015 | 333 aa | Probable lipoprotein; identified as plasminogen binding protein pgpB. | All significant hits from ε-Proteobacteria; Jonsson et al. (2004) |
| WS0865 | NP_907074.1 | 126 aa | Conserved hypothetical protein, unknown function | All significant hits from ε-Proteobacteria; missing in C. jejuni. |
| WS1039 | NP_907239 | 156 aa | Conserved hypothetical protein, unknown function | All significant hits from ε-Proteobacteria |
| WS1040 | NP_907240.1 | 236 aa | Conserved hypothetical protein, unknown function | All significant hits from ε-Proteobacteria |
| WS1235 | NP_907415 | 412 aa | Putative periplasmic protein; COG5659 | All significant hits from ε-Proteobacteria; not found in H. hepaticus. |
| WS1244 | NP_907424 | 167 aa | Putative lipoprotein | All significant hits from ε-Proteobacteria |
| WS1329 | NP_907504 | 246 aa | Putative periplasmic protein | All significant hits from ε-Proteobacteria; absent in H. pylori. |
| WS1344 | NP_907515.1 | 123 aa | Putative periplasmic protein | All significant hits from ε-Proteobacteria |
| WS1349 | NP_907520.1 | 110 aa | Probable membrane protein | All significant hits from ε-Proteobacteria |
| WS1485 | NP_907639.1 | 89 aa | Probable integral membrane protein | All significant hits from ε-Proteobacteria |
| WS1495 | NP_907647 | 87 aa | Conserved hypothetical protein, unknown function | All significant hits from ε-Proteo; The E value for C. lari (next best hit) above the threshold. |
| WS1496 | NP_907648 | 208 aa | Probable periplasmic protein | All significant hits from ε-Proteobacteria |
| WS1640 | NP_907771 | 117 aa | Probable integral membrane protein | All significant hits from ε-Proteobacteria; absent in H. pylori. |
| WS1730 | NP_907855 | 183 aa | Conserved hypothetical protein, unknown function | All significant hits from ε-Proteobacteria |
| WS1755 | NP_907877 | 168 aa | Probable lipoprotein | All significant hits from ε-Proteobacteria |
| WS1771 | NP_907893 | 183 aa | Putative membrane protein | All significant hits from ε-Proteobacteria; absent in H. pylori. |
| WS1773 | NP_907895 | 351 aa | Putative membrane protein | All significant hits from ε-Proteobacteria |
| WS1777 | NP_907899.1 | 80 aa | Conserved hypothetical protein, unknown function | All significant hits from ε-Proteobacteria |
| WS1814 | NP_907930.1 | 85 aa | Conserved hypothetical protein, unknown function | All significant hits from ε-Proteobacteria |
| WS1874 | NP_907984 | 352 aa | HolA, DNA polymerase III, delta subunit; gnl|CDD|11180, COG1466 | All significant hits except one from ε-Proteo; E value for Geo. metallireducens hit (.003). |
| WS1965 | NP_908068 | 121 aa | Conserved hypothetical protein, unknown function | All significant hits from ε-Proteobacteria |
| WS1990 | NP_908093 | 118 aa | Conserved domain DUF 177: COG1399 | All significant hits from ε-Proteobacteria |
| WS2120 | NP_908218.1 | 162 aa | Conserved hypothetical protein, unknown function | All significant hits from ε-Proteobacteria |
| WS2123 | NP_908221 | 246 aa | Conserved hypothetical protein, unknown function | All significant hits from ε-Proteobacteria |
| WS2146 | NP_908240 | 147 aa | Contains Sua5_yciO_yrdC domain involved in binding to dsRNA; gnl|CDD|15330 | All significant hits except one from ε-Proteo; E value changes from 3e-19 to 2e-4 for M. synoviae |
| WS0230 | NP_906487 | 432 aa | Show significant similarity to deacylase domain; gnl|CDD|12932, COG3608 | Besides ε-Proteo, homologs with very low E values also present in two Desulfovibrio species. |
| WS2059 | NP_908159 | 259 aa | Conserved hypothetical protein, unknown function | All significant hits from ε-Proteo; not found in T. denitrificans. |
| WS1752 | NP_907874 | 145 aa | Conserved hypothetical protein, unknown function | All significant hits from ε-Proteo; not found in C. fetus and T. denitrificans. |
| WS1211 | NP_907393 | 621 aa | Homologous to CiaB invasion antigen of C. jejuni | All significant hits from ε-Proteo; not found in H. pylori and T. denitrificans. Konkel et al. (1999) |
The species distribution of these proteins was determined by BLASTp and PSI-BLAST searches as described in the Methods section. Unless otherwise indicated all of these proteins are uniquely found in the following sequenced genomes: H. pylori 26695, H. pylori J99, H. hepaticus ATCC 51449, C. jejuni (various strains: NCTC 11168, RM1221, HB93-13, 84-25, CF93-6, 260.94, 11168 and 81-176), C. lari, C. coli, C. upsaliensis, C. fetus, W. succinogenes DSM 1740 and Thiomicrospira denitrificans ATCC 33889.