FIGURE 3.

Met apo-repressor modes calculated by elNémo. The equilibrium structure is shown in black and the structure perturbed along the three lowest frequency modes are shown in gray. (a) Lowest mode (cleft-opening): a rotation that opens a cleft in the protein at the top of figure. (b) Second lowest mode (scissor): a rotation perpendicular to the first mode that causes the monomers in the Met dimer to move respect to each other in a scissor motion. (c) Third lowest mode (rocking): a rotation about the other perpendicular axis resulting a rocking mode.