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Position parameters in calculating the first-passage time, according to Eq. 27, for the corresponding domain motion
| Rate constants | Domain moving | Domain stuck | xr | xs | xd |
|---|---|---|---|---|---|
| r1 | 1A forward (x1) | 2A (x2 = 0) | l0 | l0 | l0/3 |
| s2 | 2A backward (x2) | 1A (x1 = l0) | 0 | 0 | 2l0/3 |
| r2 | 2A forward (x2) | 1A (x1 = 0) | 0 | −l0/3 | −l0 |
| s1 | 1A backward (x1) | 2A (x2 = 0) | 0 | l0/3 | l0 |
Note that the forward direction is along −x.
